‘Ayurveda’ means ‘Science of life’. It is a holistic system of healthcare with the concept that human body is a matrix of seven basic tissues (Sapta Dhatu), three types of energies (Tridoshes) and Waste product of body (Mala). Any imbalance or disturbances in these basic principles of body cause disease. In Ayurveda, disease treatment is employed to regain the balance of basic elements and functional principles of the body.

The Charak Samhita (900 B.C.) is deemed to be as the first recorded treatise, committed to the concepts and practice of Ayurveda; its primary focus was therapeutics. This work lists 341 plants and plant products for application in medicine. The next landmark in Ayurvedic literature was the Sushruta Samhita (600 B.C.), which has special accent on surgery. It depicted 395 medicinal plants, 57 drugs of animal origin and 64 minerals and metals as therapeutic agents. Approximately 2,500 years ago another important authority in Ayurveda was Vagbhatta, who practiced around 700 A.D. His work Ashtanga Hridaya is considered peerless for the principles and practice of medicine.

The Madhava Nidana (800–900 A.D.) was the next important milestone; it is the most famous Ayurvedic work on the diagnosis of disease. The Sarangadhara Samhita (1500 A. D.) is a concise exposition of Ayurvedic principles respected for its enumeration and description of numerous formulations used in panchakarma and contains first textual reference to diagnosis by Nadi (pulse). The last celebrated writer on traditional Indian medicine was Bhava Mishra of Magadha, whose treatise Bhava Prakasha, written around 1550, is held in high esteem by modern Ayurvedic practitioners for its descriptions of about 470 medicinal plants. Other than these monumental treatises, more than 70 ‘Nighantu Granthas’ (pharmacy dictionaries of medicinal plants) and many other were written, mostly between the seventh and sixteenth century. ‘Raj Nighantu’ by Narhari Pandit and ‘Madanpala Nighantu’ by Madanpala are considered masterpieces on medicinal plants.

Ayurveda is a time-tested traditional medicinal system of India that is honored till today. Combining the strengths of the knowledge base of Ayurveda with the striking power of modern science and technology would converge to form a real discovery engine that could result in newer, safer, cheaper and effective drugs.

Thus with Ayurvedic knowledge database, the normal drug discovery course of ‘laboratories to clinics’ actually becomes ‘clinics to laboratories’ – a genuine reverse pharmacology approach. In this process safety comes first as starting point, and efficacy becomes a matter of validation. By this way, Jagshree Holistic Healthcare’s mission is to develop safe and effective products to improve quality of life.